2023WCLC早期肺癌研究进展一览,重磅进展提前看!

蓝贵评健康 2023-07-28 15:45:00
*仅供医学专业人士阅读参考

2023WCLC重点研究摘要速递!撰文 | 玖陆

世界肺癌大会(WCLC)作为肺癌领域全球规模最大的学术会议之一,即将在2023年9月9日-12日新加坡召开,世界一流的肿瘤学专家齐聚一堂,将最新的科研成果和治疗技术分享给参会者。

“医学界肿瘤频道”小编特别整理早期、局部晚期非小细胞肺癌(NSCLC)入选口头报道的大会摘要,以飨读者。

早期肺癌的创新之路

①OA11.03 一项定量分析:磨玻璃阴影和实性成分的肺癌患者亚肺叶切除术后的长期预后

Prognostic Impact of Ground Glass Opacity Component and Consolidation Size after Sublobar Resection: A Quantitative Analysis

讲者:J.Y. Kim,Asan Medical Center

②OA11.04肺癌患者进行肺段切除术前应优先评估哪些淋巴结?

Which Lymph Nodes Should be Evaluated with Priority in Segmentectomy for Lung Cancer?

讲者:J. Ichinose, A. Cancer Institute Hospital of JFCR

③OA11.05A微创手术与立体定向放疗治疗I期NSCLC的倾向匹配比较

Propensity-Matched Comparison between Minimally Invasive Surgery and Stereotactic Radiotherapy in the Treatment of Clinical Stage I NSCLC

讲者:E. Farinelli Alma Mater Studiorum-University of Bologna

④OA11.06肺段切除术 vs亚肺叶切除术治疗≤2cm高风险的NSCLC

Sublobar Resection vs. Lobectomy for Non-Small-Cell Lung Cancers 2cm or Less in Size with High-Risk Features

讲者:A.Mathey-Andrews Massachusetts General Hospital

⑤MA11.03人工智能术中诊断不明肺结节的首次人体前瞻性验证

First in Human Prospective Validation of Intraoperative Artificial Intelligence Guided Diagnosis of Indeterminate Lung Nodules

讲者:F.Azari,University of Pennsylvania

⑥MA11.04视频辅助的AI在胸腔镜肺叶切除术中的应用:手术结构解剖和相位识别

Video-Based Artificial Intelligence in Thoracoscopic Lobectomy for Lung Cancer: Surgical Structures Segmentation and Phase Recognition

讲者:H. Liang,the first affiliated hospital of Guangzhou Medical University

⑦MA11.05早期肺腺癌中长期存活和复发患者的生物免疫标记物的区别鉴定

Identification of Bio-Immune Markers that Differentiate Long-Term Survivors from Relapse in Patients with Early-Stage Lung Adenocarcinomas

讲者:Y.Lou,Mayo CLinic

⑧MA11.06肿瘤激活荧光分子用于肺癌患者术中鉴别的II期试验结果

Results from a Phase II trial of a Tumor-Activated Fluorescent Molecule for the Intra-Operative Identification of Lung Cancer

讲者:G.M. Wright,G.M. Wright

⑨MA11.08 IMpower010研究:阿替利珠单抗辅助治疗NSCLC的肿瘤突变负担和无病生存率的探索性分析

IMpower010: Exploratory Analysis of Tumour Mutational Burden and Disease-Free Survival with Adjuvant Atezolizumab in NSCLC

讲者:E. FELIP,Vall d’Hebron University Hospital

⑩MA11.09 SAKK 16/18:新辅助化疗联合度伐利尤单抗、免疫调节放疗治疗III期NSCLC的术后中期分析

SAKK 16/18: Neoadjuvant Chemotherapy, Durvalumab and Immune-Modulatory RT in Stage III(N2) NSCLC Surgical Interim Analysis.

讲者:P. Dorn,Inselspital, Bern University Hospital

⑪MA11.10静脉注射吲哚菁绿在肺段切除术中的应用

Intravenous Indocyanine Green Administration Provides Sufficient Margins in Pulmonary Segmentectomy

讲者:T. Ochi,Chiba University Graduate School of Medicine

⑫MA11.11奥希替尼新辅助治疗可切除EGFR突变NSCLC的耐药持久性 (NORA研究)

Drug Tolerant Persister Cells to Neoadjuvant Osimertinib in Resectable Non-small Cell Lung Cancer Harboring EGFR Mutations (NORA)

讲者:J.B.Yonsei Cancer Center, Yonsei University College of Medicine

突破界限:早期NSCLC辅助治疗和新辅助治疗

①OA12.03 一项比较肺叶切除术和亚肺叶切除术治疗T1aN0 NSCLC后的第二原发性肺癌发病率分析(CALGB 140503)

An Analysis of the Rate of Second Primary Lung Cancer from CALGB (Alliance) 140503 Trial of Lobar versus Sub-Lobar Resection for T1aN0 NSCLC

讲者:T.E. Stinchcombe Duke Cancer Institute

②OA12.04立体定向消融放疗后联合纳武利尤单抗治疗早期NSCLC:i-SABR 随机试验

Nivolumab After Stereotactic Ablative Radiotherapy for Early-Stage Non-Small Cell Lung Cancer: Randomized I-SABR Trial

讲者:张玉蛟教授,美国MD安德森癌症中心

③OA12.05 度伐利尤单抗+化疗术前新辅助治疗,以及度伐利尤单抗术后辅助治疗可切除NSCLC的手术预后结果(AEGEAN研究)

Surgical Outcomes with Neoadjuvant Durvalumab + Chemotherapy Followed by Adjuvant Durvalumab in Resectable NSCLC (AEGEAN)

讲者:T.Mitsudomi,Division of Thoracic Surgery

④OA12.06度伐利尤单抗+化疗新辅助治疗,随后度伐利尤单抗辅助治疗可切除EGFR突变NSCLC(AEGEAN研究)

Neoadjuvant Durvalumab + Chemotherapy Followed by Adjuvant Durvalumab in Resectable EGFR-mutated NSCLC (AEGEAN)

讲者:J. He,中国医学科学院肿瘤医院

开启可切除III期NSCLC治疗新纪元

①OA06.03 可切除III期NSCLC的国际EORTC调研

An International EORTC Survey on Resectability of Stage III Non-small Cell Lung Cancer

讲者:I.Houda,Amsterdam University Medical Centers

②OA06.04可切除NSCLC术后免疫联合放化疗新辅助治疗的疗效:INCREASE试验

Surgery after Neoadjuvant Immuno-Chemoradiotherapy in (Borderline) Resectable NSCLC: Results from the INCREASE Trial

讲者:A.Dickhoff, D,Amsterdam University Medical Center

③OA06.05可切除III期NSCLC共识定义:EORTC-肺癌组与其他科学学会的倡议

Consensual Definition of Stage III NSCLC Resectability: EORTC-Lung Cancer Group Initiative with Other Scientific Societies

讲者:A-M. Dingemans,Erasmus MC

④OA06.06:新型多参数生物标志物评估免疫新辅助治疗NSCLC的病理缓解疗效:一项真实世界研究

A Novel Multiparameter Biomarker of Pathological Response for NSCLC Receiving Neoadjuvant Immunotherapy: A Real-world Study

讲者:S. Wu,广东省人民医院

⑤MA16.03 Tremelimumab+度伐利尤单抗后接受放化疗治疗不可切除局部晚期NSCLC的诱导试验

Tremelimumab plus Durvalumab Prior to Chemoradiotherapy in Unresectable Locally Advanced NSCLC, the Induction Trial.

讲者:M.M. Smeenk,Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital

⑥MA16.04 ctDNA的NGS定量检测应与所用方法相适应

Circulating Tumor DNA Quantification by NGS Should Be Adapted to the Methodology Used

讲者:R. Serna Blasco,ospital Universitario Puerta de Hierro-Majadahonda

⑦MA16.05 低剂量放疗、化疗联合度伐利尤单抗新辅助治疗潜在可切除III期NSCLC的Ib期试验

Phase Ib Trial of Neoadjuvant Low Dose Radiotherapy, Chemotherapy, and Durvalumab for Potentially Resectable Stage III NSCLC

讲者:J. Li,Sichuan Clinical Research Center for Cancer

⑧MA16.08 MR引导的大分割放疗和同步化疗治疗局部晚期NSCLC的疗效

The Efficacy of MR-Guided Hypo-Fractionated Radiotherapy and Concurrent Chemotherapy in Locally Advanced Non-Small Cell Lung Cancer

讲者:H. Liu,Sun Yat-sen University Cancer Center

⑨MA16.09 基于CT的AI预测在NSCLC良恶性MLN的诊断价值

Evaluation of the Diagnostic Performance of AI Accompanied by CT Images in the Differentiation of Malignant or Benign MLN in NSCLC

讲者:Y. KAHYA,Ankara University Faculty of Medicine

⑩MA16.10 II期PRoT-BM试验的5年随访结果更新

An Update 5 Years of Randomized Phase 2 Study (PRoT-BM Trial)

讲者:O. Arrieta,Instituto Nacional de Cancerología

局部晚期NSCLC未来发展之路

①OA17.03度伐利尤单抗治疗放化疗后III期不可切除EGFR突变NSCLC的真实世界结果(PACIFIC-R研究)

Real-World Outcomes with Durvalumab After Chemoradiotherapy in Unresectable Stage III EGFR-Mutated NSCLC (PACIFIC-R)

讲者:S. Peters,Department of Oncology, Centre Hospitalier Universitaire Vaudois

②OA17.04放疗对局部晚期NSCLC的长期临床结果:NRG Oncology-RTOG 0617的5年二次分析结果

Long-Term Outcomes by Radiation Technique for Locally-Advanced Non-small Lung Cancer: A Secondary Analysis of NRG Oncology-RTOG 0617 at 5-years

讲者:S.G. Chun, MD Anderson

③OA17.05 NRG-RTOG 0617转化分析:免疫生物标志物与III期NSCLC生存率的关联

Association Between Pre-Treatment Circulating Immune Biomarkers And Survival In Stage III NSCLC: A Translational Analysis From NRG-RTOG 0617

讲者:M.Machtay,Penn State University Cancer Institute

④OA17.06 PD-L1表达在放化疗治疗不可切除III期NSCLC的预测价值

The Predictive Value of PD-L1 levels on Circulating Stromal Cells in Unresectable Stage 3 NSCLC Treated with Chemoradiation

讲者:S. Lin,The University of Texas MD Anderson Cancer Center

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